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Vasoactive intestinal peptide-expressing interneurons are impaired in a mouse model of Dravet syndrome

Dravet Syndrome (DS) is a severe neurodevelopmental disorder caused by pathogenic loss of function variants in the gene SCN1A which encodes the voltage gated sodium (Na(+)) channel subunit Nav1.1. GABAergic interneurons expressing parvalbumin (PV-INs) and somatostatin (SST-INs) exhibit impaired exci...

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Detalles Bibliográficos
Autores principales:	Goff, Kevin M, Goldberg, Ethan M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629374/ https://www.ncbi.nlm.nih.gov/pubmed/31282864 http://dx.doi.org/10.7554/eLife.46846

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