Poorly controlled diabetes during pregnancy and lactation activates the Foxo1 pathway and causes glucose intolerance in adult offspring

Exposure to maternal diabetes during pregnancy results in diabetes in offspring, but its underlying mechanisms are unclear. Here, we investigated the phenotype and molecular defects of the offspring of poorly controlled diabetic female mice generated by streptozotocin (STZ) administration. Offspring...

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Detalles Bibliográficos
Autores principales: Inoguchi, Yukihiro, Ichiyanagi, Kenji, Ohishi, Hiroaki, Maeda, Yasutaka, Sonoda, Noriyuki, Ogawa, Yoshihiro, Inoguchi, Toyoshi, Sasaki, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629688/
https://www.ncbi.nlm.nih.gov/pubmed/31308441
http://dx.doi.org/10.1038/s41598-019-46638-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629688/
https://www.ncbi.nlm.nih.gov/pubmed/31308441
http://dx.doi.org/10.1038/s41598-019-46638-2

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