Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer

Long noncoding RNAs (lncRNAs) have emerged as critical regulators of tumorigenesis, and yet their mechanistic roles remain challenging to characterize. Here, we integrate functional proteomics with lncRNA-interactome profiling to characterize Urothelial Cancer Associated 1 (UCA1), a candidate driver...

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Detalles Bibliográficos
Autores principales: Lin, Xianzhi, Spindler, Tassja J., de Souza Fonseca, Marcos Abraão, Corona, Rosario I., Seo, Ji-Heui, Dezem, Felipe Segato, Li, Lewyn, Lee, Janet M., Long, Henry W., Sellers, Thomas A., Karlan, Beth Y., Noushmehr, Houtan, Freedman, Matthew L., Gayther, Simon A., Lawrenson, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629722/
https://www.ncbi.nlm.nih.gov/pubmed/31307004
http://dx.doi.org/10.1016/j.isci.2019.06.025

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