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Quantitative bioimage analytics enables measurement of targeted cellular stress response induced by celastrol-loaded nanoparticles
The cellular stress response, which provides protection against proteotoxic stresses, is characterized by the activation of heat shock factor 1 and the formation of nuclear stress bodies (nSBs). In this study, we developed a computerized method to quantify the formation and size distribution of nSBs...
Autores principales: | Niemelä, Erik, Desai, Diti, Lundsten, Emine, Rosenholm, Jessica M., Kankaanpää, Pasi, Eriksson, John E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629742/ https://www.ncbi.nlm.nih.gov/pubmed/31079284 http://dx.doi.org/10.1007/s12192-019-00999-9 |
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