Sleeping Beauty Mouse Models of Cancer: Microenvironmental Influences on Cancer Genetics

The Sleeping Beauty (SB) transposon insertional mutagenesis system offers a streamlined approach to identify genetic drivers of cancer. With a relatively random insertion profile, SB is uniquely positioned for conducting unbiased forward genetic screens. Indeed, SB mouse models of cancer have reveal...

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Detalles Bibliográficos
Autores principales: Guimaraes-Young, Amy, Feddersen, Charlotte R., Dupuy, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629774/
https://www.ncbi.nlm.nih.gov/pubmed/31338332
http://dx.doi.org/10.3389/fonc.2019.00611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629774/
https://www.ncbi.nlm.nih.gov/pubmed/31338332
http://dx.doi.org/10.3389/fonc.2019.00611

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