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Sleeping Beauty Mouse Models of Cancer: Microenvironmental Influences on Cancer Genetics

The Sleeping Beauty (SB) transposon insertional mutagenesis system offers a streamlined approach to identify genetic drivers of cancer. With a relatively random insertion profile, SB is uniquely positioned for conducting unbiased forward genetic screens. Indeed, SB mouse models of cancer have reveal...

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Detalles Bibliográficos
Autores principales:	Guimaraes-Young, Amy, Feddersen, Charlotte R., Dupuy, Adam J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629774/ https://www.ncbi.nlm.nih.gov/pubmed/31338332 http://dx.doi.org/10.3389/fonc.2019.00611

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