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Polynuclear ruthenium organometallic compounds induce DNA damage in human cells identified by the nucleotide excision repair factor XPC

Ruthenium organometallic compounds represent an attractive avenue in developing alternatives to platinum-based chemotherapeutic agents. While evidence has been presented indicating ruthenium-based compounds interact with isolated DNA in vitro, it is unclear what effect these compounds exert in cells...

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Detalles Bibliográficos
Autores principales:	Fast, Olivia G., Gentry, Brittany, Strouth, Liah, Niece, Madison B., Beckford, Floyd A., Shell, Steven M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629949/ https://www.ncbi.nlm.nih.gov/pubmed/31227614 http://dx.doi.org/10.1042/BSR20190378

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