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Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors

Preexisting immunity against adeno-associated virus (AAV) is a major challenge facing AAV gene therapy, resulting in the exclusion of patients from clinical trials. Accordingly, proper assessment of anti-AAV immunity is necessary for understanding clinical data and for product development. Previous...

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Detalles Bibliográficos
Autores principales: Kruzik, Anita, Fetahagic, Damir, Hartlieb, Bettina, Dorn, Sebastian, Koppensteiner, Herwig, Horling, Frank M., Scheiflinger, Friedrich, Reipert, Birgit M., de la Rosa, Maurus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629972/
https://www.ncbi.nlm.nih.gov/pubmed/31338384
http://dx.doi.org/10.1016/j.omtm.2019.05.014