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Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors
Preexisting immunity against adeno-associated virus (AAV) is a major challenge facing AAV gene therapy, resulting in the exclusion of patients from clinical trials. Accordingly, proper assessment of anti-AAV immunity is necessary for understanding clinical data and for product development. Previous...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629972/ https://www.ncbi.nlm.nih.gov/pubmed/31338384 http://dx.doi.org/10.1016/j.omtm.2019.05.014 |