The absence of NIPA2 enhances neural excitability through BK (big potassium) channels

AIM: To reveal the pathogenesis and find the precision treatment for the childhood absence epilepsy (CAE) patients with NIPA2 mutations. METHODS: We performed whole‐cell patch‐clamp recordings to measure the electrophysiological properties of layer V neocortical somatosensory pyramidal neurons in wi...

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Detalles Bibliográficos
Autores principales: Liu, Na‐Na, Xie, Han, Xiang‐wei, Wen‐Shu, Gao, Kai, Wang, Tian‐Shuang, Jiang, Yu‐Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630003/
https://www.ncbi.nlm.nih.gov/pubmed/30895737
http://dx.doi.org/10.1111/cns.13119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630003/
https://www.ncbi.nlm.nih.gov/pubmed/30895737
http://dx.doi.org/10.1111/cns.13119

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