Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome

A 40-year-old man suffered from short bowel syndrome. Since a large amount of intestinal output and watery diarrhea hampered his quality of life, we tried to control the intestinal output by reducing the secretion of gastric acid with lansoprazole. Because the small intestine was only 10 cm in lengt...

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Autores principales: Yoshioka, Masato, Watanabe, Tasuku, Iida, Masatake, Nakagawa, Yasuhiko, Uchinami, Hiroshi, Watanabe, Go, Abe, Yuki, Yagi, Fumitaka, Yokoyama, Naohiro, Yamamoto, Yuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630122/
https://www.ncbi.nlm.nih.gov/pubmed/30799357
http://dx.doi.org/10.2169/internalmedicine.2221-18
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author Yoshioka, Masato
Watanabe, Tasuku
Iida, Masatake
Nakagawa, Yasuhiko
Uchinami, Hiroshi
Watanabe, Go
Abe, Yuki
Yagi, Fumitaka
Yokoyama, Naohiro
Yamamoto, Yuzo
author_facet Yoshioka, Masato
Watanabe, Tasuku
Iida, Masatake
Nakagawa, Yasuhiko
Uchinami, Hiroshi
Watanabe, Go
Abe, Yuki
Yagi, Fumitaka
Yokoyama, Naohiro
Yamamoto, Yuzo
author_sort Yoshioka, Masato
collection PubMed
description A 40-year-old man suffered from short bowel syndrome. Since a large amount of intestinal output and watery diarrhea hampered his quality of life, we tried to control the intestinal output by reducing the secretion of gastric acid with lansoprazole. Because the small intestine was only 10 cm in length and effective absorption of oral lansoprazole was doubtful, we monitored his intragastric pH for 24 hours and confirmed that the holding time above pH 3.0 was 14.5 hours (60.4%). He spent his home life eating porridge during the day, and receiving total parenteral nutrition of 1,100 mL/day at night while taking lansoprazole as an oral tablet (30 mg) once a day.
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spelling pubmed-66301222019-07-17 Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome Yoshioka, Masato Watanabe, Tasuku Iida, Masatake Nakagawa, Yasuhiko Uchinami, Hiroshi Watanabe, Go Abe, Yuki Yagi, Fumitaka Yokoyama, Naohiro Yamamoto, Yuzo Intern Med Case Report A 40-year-old man suffered from short bowel syndrome. Since a large amount of intestinal output and watery diarrhea hampered his quality of life, we tried to control the intestinal output by reducing the secretion of gastric acid with lansoprazole. Because the small intestine was only 10 cm in length and effective absorption of oral lansoprazole was doubtful, we monitored his intragastric pH for 24 hours and confirmed that the holding time above pH 3.0 was 14.5 hours (60.4%). He spent his home life eating porridge during the day, and receiving total parenteral nutrition of 1,100 mL/day at night while taking lansoprazole as an oral tablet (30 mg) once a day. The Japanese Society of Internal Medicine 2019-02-25 2019-06-15 /pmc/articles/PMC6630122/ /pubmed/30799357 http://dx.doi.org/10.2169/internalmedicine.2221-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yoshioka, Masato
Watanabe, Tasuku
Iida, Masatake
Nakagawa, Yasuhiko
Uchinami, Hiroshi
Watanabe, Go
Abe, Yuki
Yagi, Fumitaka
Yokoyama, Naohiro
Yamamoto, Yuzo
Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome
title Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome
title_full Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome
title_fullStr Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome
title_full_unstemmed Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome
title_short Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome
title_sort effect of lansoprazole on the control of the intragastric ph in a patient with short bowel syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630122/
https://www.ncbi.nlm.nih.gov/pubmed/30799357
http://dx.doi.org/10.2169/internalmedicine.2221-18
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