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Technical design and concept of a 0.35 T MR-Linac

The integration of magnetic resonance (MR) imaging and linear accelerators into hybrid treatment systems has made MR-guided radiation therapy a clinical reality. This work summarizes the technical design of a 0.35 T MR-Linac and corresponding clinical concepts. The system facilitates 3D-conformal as...

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Autor principal: Klüter, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630153/
https://www.ncbi.nlm.nih.gov/pubmed/31341983
http://dx.doi.org/10.1016/j.ctro.2019.04.007
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author Klüter, Sebastian
author_facet Klüter, Sebastian
author_sort Klüter, Sebastian
collection PubMed
description The integration of magnetic resonance (MR) imaging and linear accelerators into hybrid treatment systems has made MR-guided radiation therapy a clinical reality. This work summarizes the technical design of a 0.35 T MR-Linac and corresponding clinical concepts. The system facilitates 3D-conformal as well as IMRT treatments with 6MV photons. Daily MR imaging provides superior soft-tissue contrast for patient setup and also enables on-table adaption of treatment plans, which is fully integrated into the treatment workflow of the system. Automated beam gating during delivery is facilitated by cine MR imaging and structure tracking. Combining different novel features compared to conventional image-guided radiotherapy, this technology offers the potential for margin reduction as well as dose escalation.
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spelling pubmed-66301532019-07-24 Technical design and concept of a 0.35 T MR-Linac Klüter, Sebastian Clin Transl Radiat Oncol Article The integration of magnetic resonance (MR) imaging and linear accelerators into hybrid treatment systems has made MR-guided radiation therapy a clinical reality. This work summarizes the technical design of a 0.35 T MR-Linac and corresponding clinical concepts. The system facilitates 3D-conformal as well as IMRT treatments with 6MV photons. Daily MR imaging provides superior soft-tissue contrast for patient setup and also enables on-table adaption of treatment plans, which is fully integrated into the treatment workflow of the system. Automated beam gating during delivery is facilitated by cine MR imaging and structure tracking. Combining different novel features compared to conventional image-guided radiotherapy, this technology offers the potential for margin reduction as well as dose escalation. Elsevier 2019-04-08 /pmc/articles/PMC6630153/ /pubmed/31341983 http://dx.doi.org/10.1016/j.ctro.2019.04.007 Text en © 2019 The Author http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Klüter, Sebastian
Technical design and concept of a 0.35 T MR-Linac
title Technical design and concept of a 0.35 T MR-Linac
title_full Technical design and concept of a 0.35 T MR-Linac
title_fullStr Technical design and concept of a 0.35 T MR-Linac
title_full_unstemmed Technical design and concept of a 0.35 T MR-Linac
title_short Technical design and concept of a 0.35 T MR-Linac
title_sort technical design and concept of a 0.35 t mr-linac
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630153/
https://www.ncbi.nlm.nih.gov/pubmed/31341983
http://dx.doi.org/10.1016/j.ctro.2019.04.007
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