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Application of Size and Maturation Functions to Population Pharmacokinetic Modeling of Pediatric Patients

Traditionally, dosage for pediatric patients has been optimized using simple weight-scaled methods, but these methods do not always meet the requirements of children. To overcome this discrepancy, population pharmacokinetic (PK) modeling of size and maturation functions has been proposed. The main o...

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Detalles Bibliográficos
Autores principales: Back, Hyun-moon, Lee, Jong Bong, Han, Nayoung, Goo, Sungwoo, Jung, Eben, Kim, Junyeong, Song, Byungjeong, An, Sook Hee, Kim, Jung Tae, Rhie, Sandy Jeong, Ree, Yoon Sun, Chae, Jung-woo, Kim, JaeWoo, Yun, Hwi-yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630378/
https://www.ncbi.nlm.nih.gov/pubmed/31163633
http://dx.doi.org/10.3390/pharmaceutics11060259