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Degradation Behavior In Vitro of Carbon Nanotubes (CNTs)/Poly(lactic acid) (PLA) Composite Suture

Poly(lactic acid) (PLA) suture can be absorbed by the human body, and so have wide applications in modern surgery operations. The degradation period of PLA suture is expected to meet with the healing time of different types of wounds. In order to control the degradation period of the PLA suture, the...

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Autores principales: Liu, Shuqiang, Wu, Gaihong, Chen, Xiaogang, Zhang, Xiaofang, Yu, Juanjuan, Liu, Mingfang, Zhang, Yao, Wang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630379/
https://www.ncbi.nlm.nih.gov/pubmed/31181799
http://dx.doi.org/10.3390/polym11061015
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author Liu, Shuqiang
Wu, Gaihong
Chen, Xiaogang
Zhang, Xiaofang
Yu, Juanjuan
Liu, Mingfang
Zhang, Yao
Wang, Peng
author_facet Liu, Shuqiang
Wu, Gaihong
Chen, Xiaogang
Zhang, Xiaofang
Yu, Juanjuan
Liu, Mingfang
Zhang, Yao
Wang, Peng
author_sort Liu, Shuqiang
collection PubMed
description Poly(lactic acid) (PLA) suture can be absorbed by the human body, and so have wide applications in modern surgery operations. The degradation period of PLA suture is expected to meet with the healing time of different types of wounds. In order to control the degradation period of the PLA suture, the carbon nanotubes (CNTs) were composited with PLA suture, and the degradation experiment in vitro was performed on sutures. The structure and properties of sutures during degradation, such as surface morphology, breaking strength, elongation, mass and chemical structure, were tracked and analyzed. The results indicated that the degradation brought about surface defects and resulted in 13.5 weeks for the strength valid time of the original PLA suture. By contrast, the strength valid time of the CNTs/PLA suture was increased to 26.6 weeks. Whilst the toughness of both the pure PLA and CNTs/PLA sutures decreased rapidly and almost disappeared after 3 to 4 weeks of degradation. The mass loss demonstrated that the time required for complete degradation of the two sutures was obviously different, the pure PLA suture 49 weeks, while CNTs/PLA sutures 63 to 73 weeks. The research proved that CNTs delayed PLA degradation and prolonged its strength valid time in degradation.
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spelling pubmed-66303792019-08-19 Degradation Behavior In Vitro of Carbon Nanotubes (CNTs)/Poly(lactic acid) (PLA) Composite Suture Liu, Shuqiang Wu, Gaihong Chen, Xiaogang Zhang, Xiaofang Yu, Juanjuan Liu, Mingfang Zhang, Yao Wang, Peng Polymers (Basel) Article Poly(lactic acid) (PLA) suture can be absorbed by the human body, and so have wide applications in modern surgery operations. The degradation period of PLA suture is expected to meet with the healing time of different types of wounds. In order to control the degradation period of the PLA suture, the carbon nanotubes (CNTs) were composited with PLA suture, and the degradation experiment in vitro was performed on sutures. The structure and properties of sutures during degradation, such as surface morphology, breaking strength, elongation, mass and chemical structure, were tracked and analyzed. The results indicated that the degradation brought about surface defects and resulted in 13.5 weeks for the strength valid time of the original PLA suture. By contrast, the strength valid time of the CNTs/PLA suture was increased to 26.6 weeks. Whilst the toughness of both the pure PLA and CNTs/PLA sutures decreased rapidly and almost disappeared after 3 to 4 weeks of degradation. The mass loss demonstrated that the time required for complete degradation of the two sutures was obviously different, the pure PLA suture 49 weeks, while CNTs/PLA sutures 63 to 73 weeks. The research proved that CNTs delayed PLA degradation and prolonged its strength valid time in degradation. MDPI 2019-06-08 /pmc/articles/PMC6630379/ /pubmed/31181799 http://dx.doi.org/10.3390/polym11061015 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Liu, Shuqiang
Wu, Gaihong
Chen, Xiaogang
Zhang, Xiaofang
Yu, Juanjuan
Liu, Mingfang
Zhang, Yao
Wang, Peng
Degradation Behavior In Vitro of Carbon Nanotubes (CNTs)/Poly(lactic acid) (PLA) Composite Suture
title Degradation Behavior In Vitro of Carbon Nanotubes (CNTs)/Poly(lactic acid) (PLA) Composite Suture
title_full Degradation Behavior In Vitro of Carbon Nanotubes (CNTs)/Poly(lactic acid) (PLA) Composite Suture
title_fullStr Degradation Behavior In Vitro of Carbon Nanotubes (CNTs)/Poly(lactic acid) (PLA) Composite Suture
title_full_unstemmed Degradation Behavior In Vitro of Carbon Nanotubes (CNTs)/Poly(lactic acid) (PLA) Composite Suture
title_short Degradation Behavior In Vitro of Carbon Nanotubes (CNTs)/Poly(lactic acid) (PLA) Composite Suture
title_sort degradation behavior in vitro of carbon nanotubes (cnts)/poly(lactic acid) (pla) composite suture
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630379/
https://www.ncbi.nlm.nih.gov/pubmed/31181799
http://dx.doi.org/10.3390/polym11061015
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