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Role of Evolutionary Selection Acting on Vaccine Antigens in the Re-Emergence of Bordetella Pertussis

Pertussis (“whooping cough”) is a re-emerging disease with increasing incidence among fully vaccinated individuals. We explored the genetic diversity of five Bordetella pertussis proteins used to generate the subunit vaccine across ancestral and newly emergent strains using immunoinformatics and evo...

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Detalles Bibliográficos
Autores principales: Etskovitz, Haley, Anastasio, Nicole, Green, Evangeline, May, Meghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630436/
https://www.ncbi.nlm.nih.gov/pubmed/30995764
http://dx.doi.org/10.3390/diseases7020035

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