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Mechanically Robust Gastroretentive Drug-Delivery Systems Capable of Controlling Dissolution Behaviors of Coground β-Lapachone

In this study, we aimed to design a highly swellable and mechanically robust matrix tablet (SMT) as a gastroretentive drug-delivery system (GRDDS) capable of improving the dissolution behavior of β-lapachone with low aqueous solubility. For the preparation of SMTs, the cogrinding technique and freez...

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Detalles Bibliográficos
Autores principales:	Kim, Hyeongmin, Lee, Chung-Lyol, Lee, Seohyun, Lee, Tae Jin, Haleem, Iqra, Lee, Younghong, Hwang, Na Jung, Shim, Kyusun, Kim, Dohyun, Lee, Jaehwi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630442/ https://www.ncbi.nlm.nih.gov/pubmed/31185692 http://dx.doi.org/10.3390/pharmaceutics11060271

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