Anomeric Spironucleosides of β-d-Glucopyranosyl Uracil as Potential Inhibitors of Glycogen Phosphorylase

In the case of type 2 diabetes, inhibitors of glycogen phosphorylase (GP) may prevent unwanted glycogenolysis under high glucose conditions and thus aim at the reduction of excessive glucose production by the liver. Anomeric spironucleosides, such as hydantocidin, present a rich synthetic chemistry...

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Detalles Bibliográficos
Autores principales: Stathi, Aggeliki, Mamais, Michael, Chrysina, Evangelia D., Gimisis, Thanasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630470/
https://www.ncbi.nlm.nih.gov/pubmed/31242546
http://dx.doi.org/10.3390/molecules24122327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630470/
https://www.ncbi.nlm.nih.gov/pubmed/31242546
http://dx.doi.org/10.3390/molecules24122327

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