Cargando…
Anomeric Spironucleosides of β-d-Glucopyranosyl Uracil as Potential Inhibitors of Glycogen Phosphorylase
In the case of type 2 diabetes, inhibitors of glycogen phosphorylase (GP) may prevent unwanted glycogenolysis under high glucose conditions and thus aim at the reduction of excessive glucose production by the liver. Anomeric spironucleosides, such as hydantocidin, present a rich synthetic chemistry...
Autores principales: | Stathi, Aggeliki, Mamais, Michael, Chrysina, Evangelia D., Gimisis, Thanasis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630470/ https://www.ncbi.nlm.nih.gov/pubmed/31242546 http://dx.doi.org/10.3390/molecules24122327 |
Ejemplares similares
-
Synthesis, Kinetic and Conformational Studies of 2-Substituted-5-(β-d-glucopyranosyl)-pyrimidin-4-ones as Potential Inhibitors of Glycogen Phosphorylase
por: Mavreas, Konstantinos F., et al.
Publicado: (2020) -
Synthesis of New C- and N-β-d-Glucopyranosyl Derivatives of Imidazole, 1,2,3-Triazole and Tetrazole, and Their Evaluation as Inhibitors of Glycogen Phosphorylase
por: Kun, Sándor, et al.
Publicado: (2018) -
Design and Synthesis of 3-(β-d-Glucopyranosyl)-4-amino/4-guanidino Pyrazole Derivatives and Analysis of Their Glycogen Phosphorylase Inhibitory Potential
por: Kun, Sándor, et al.
Publicado: (2023) -
Synthesis of Spironucleosides: Past and Future Perspectives
por: Soengas, Raquel G., et al.
Publicado: (2017) -
Glycogen Phosphorylase Inhibitor N-(3,5-Dimethyl-Benzoyl)-N’-(β-D-Glucopyranosyl)Urea Improves Glucose Tolerance under Normoglycemic and Diabetic Conditions and Rearranges Hepatic Metabolism
por: Nagy, Lilla, et al.
Publicado: (2013)