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Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington’s Disease

Huntington’s disease (HD) is a neurodegenerative disorder caused by an expanded CAG repeat in exon 1 of the HTT gene. HD usually manifests in mid-life with loss of GABAergic projection neurons from the striatum accompanied by progressive atrophy of the putamen followed by other brain regions, but li...

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Detalles Bibliográficos
Autores principales:	Patassini, Stefano, Begley, Paul, Xu, Jingshu, Church, Stephanie J., Kureishy, Nina, Reid, Suzanne J., Waldvogel, Henry J., Faull, Richard L. M., Snell, Russell G., Unwin, Richard D., Cooper, Garth J. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630497/ https://www.ncbi.nlm.nih.gov/pubmed/31212603 http://dx.doi.org/10.3390/metabo9060113

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