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Epigenetic Factors of Disease
The development of tissues involves the direction of specific programs for gene expression among distinct cell types. These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. Thus, the broad synchronization in pattern...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630624/ https://www.ncbi.nlm.nih.gov/pubmed/31197091 http://dx.doi.org/10.3390/diseases7020042 |
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author | Alshiraihi, Ilham Brown, Mark A. |
author_facet | Alshiraihi, Ilham Brown, Mark A. |
author_sort | Alshiraihi, Ilham |
collection | PubMed |
description | The development of tissues involves the direction of specific programs for gene expression among distinct cell types. These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. Thus, the broad synchronization in patterns of gene expression ultimately dictates cellular consequences. Aberrations in these epigenetic mechanisms are known to be associated with a range of diseases. Herein, we highlight epigenetic factors that, when aberrantly expressed, lead to a broad range of diseases. Further, we call upon the community of biomedical researchers to share their findings related to the epigenetic factors of disease. |
format | Online Article Text |
id | pubmed-6630624 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66306242019-08-19 Epigenetic Factors of Disease Alshiraihi, Ilham Brown, Mark A. Diseases Editorial The development of tissues involves the direction of specific programs for gene expression among distinct cell types. These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. Thus, the broad synchronization in patterns of gene expression ultimately dictates cellular consequences. Aberrations in these epigenetic mechanisms are known to be associated with a range of diseases. Herein, we highlight epigenetic factors that, when aberrantly expressed, lead to a broad range of diseases. Further, we call upon the community of biomedical researchers to share their findings related to the epigenetic factors of disease. MDPI 2019-06-14 /pmc/articles/PMC6630624/ /pubmed/31197091 http://dx.doi.org/10.3390/diseases7020042 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Editorial Alshiraihi, Ilham Brown, Mark A. Epigenetic Factors of Disease |
title | Epigenetic Factors of Disease |
title_full | Epigenetic Factors of Disease |
title_fullStr | Epigenetic Factors of Disease |
title_full_unstemmed | Epigenetic Factors of Disease |
title_short | Epigenetic Factors of Disease |
title_sort | epigenetic factors of disease |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630624/ https://www.ncbi.nlm.nih.gov/pubmed/31197091 http://dx.doi.org/10.3390/diseases7020042 |
work_keys_str_mv | AT alshiraihiilham epigeneticfactorsofdisease AT brownmarka epigeneticfactorsofdisease |