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Epigenetic Factors of Disease

The development of tissues involves the direction of specific programs for gene expression among distinct cell types. These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. Thus, the broad synchronization in pattern...

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Detalles Bibliográficos
Autores principales: Alshiraihi, Ilham, Brown, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630624/
https://www.ncbi.nlm.nih.gov/pubmed/31197091
http://dx.doi.org/10.3390/diseases7020042
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author Alshiraihi, Ilham
Brown, Mark A.
author_facet Alshiraihi, Ilham
Brown, Mark A.
author_sort Alshiraihi, Ilham
collection PubMed
description The development of tissues involves the direction of specific programs for gene expression among distinct cell types. These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. Thus, the broad synchronization in patterns of gene expression ultimately dictates cellular consequences. Aberrations in these epigenetic mechanisms are known to be associated with a range of diseases. Herein, we highlight epigenetic factors that, when aberrantly expressed, lead to a broad range of diseases. Further, we call upon the community of biomedical researchers to share their findings related to the epigenetic factors of disease.
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spelling pubmed-66306242019-08-19 Epigenetic Factors of Disease Alshiraihi, Ilham Brown, Mark A. Diseases Editorial The development of tissues involves the direction of specific programs for gene expression among distinct cell types. These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. Thus, the broad synchronization in patterns of gene expression ultimately dictates cellular consequences. Aberrations in these epigenetic mechanisms are known to be associated with a range of diseases. Herein, we highlight epigenetic factors that, when aberrantly expressed, lead to a broad range of diseases. Further, we call upon the community of biomedical researchers to share their findings related to the epigenetic factors of disease. MDPI 2019-06-14 /pmc/articles/PMC6630624/ /pubmed/31197091 http://dx.doi.org/10.3390/diseases7020042 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Editorial
Alshiraihi, Ilham
Brown, Mark A.
Epigenetic Factors of Disease
title Epigenetic Factors of Disease
title_full Epigenetic Factors of Disease
title_fullStr Epigenetic Factors of Disease
title_full_unstemmed Epigenetic Factors of Disease
title_short Epigenetic Factors of Disease
title_sort epigenetic factors of disease
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630624/
https://www.ncbi.nlm.nih.gov/pubmed/31197091
http://dx.doi.org/10.3390/diseases7020042
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