Cargando…

Antiproliferative Benzoindazolequinones as Potential Cyclooxygenase-2 Inhibitors

Quinones and nitrogen heterocyclic moieties have been recognized as important pharmacophores in the development of antitumor agents. This study aimed to establish whether there was any correlation between the in silico predicted parameters and the in vitro antiproliferative activity of a family of b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Molinari, Aurora, Oliva, Alfonso, Arismendi-Macuer, Marlene, Guzmán, Leda, Acevedo, Waldo, Aguayo, Daniel, Vinet, Raúl, San Feliciano, Arturo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630654/ https://www.ncbi.nlm.nih.gov/pubmed/31216654 http://dx.doi.org/10.3390/molecules24122261

Ejemplares similares

New 1H-Benzo[f]indazole-4,9-diones Conjugated with C-Protected Amino Acids and Other Derivatives: Synthesis and in Vitro Antiproliferative Evaluation
por: Molinari, Aurora, et al.
Publicado: (2015)

2-Acetyl-5,8-dihydro-6-(4-methyl-3-pentenyl)-1,4-naphthohydroquinone-Derived Chalcones as Potential Anticancer Agents
por: Maldonado, Javier, et al.
Publicado: (2023)

Cyclooxygenase-2 overexpression abrogates the antiproliferative effects of TGF-β
por: Enders, G A
Publicado: (2007)

Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: a promising tool for early detection of COPD and lung cancer in smokers
por: Guzmán, Leda, et al.
Publicado: (2012)

In vitro evaluation and molecular docking of QS-21 and quillaic acid from Quillaja saponaria Molina as gastric cancer agents
por: Guzmán, Leda, et al.
Publicado: (2020)

11-Oxoeicosatetraenoic Acid Is a Cyclooxygenase-2/15-Hydroxyprostaglandin Dehydrogenase-Derived Antiproliferative Eicosanoid
por: Liu, Xiaojing, et al.
Publicado: (2011)

Cannabinoid system and cyclooxygenases inhibitors
por: Păunescu, H, et al.
Publicado: (2011)

Genetic diversity and biological activity of Curcuma longa ecotypes from Rapa Nui using molecular markers
por: Balada, Cristóbal, et al.
Publicado: (2021)

Cyclooxygenase-2 inhibitors: promise or peril?
por: Mengle-Gaw, Laurel J, et al.
Publicado: (2002)

Cyclooxygenase (COX) Inhibitors and the Newborn Kidney
por: Smith, Francine G., et al.
Publicado: (2012)

Colorectal Carcinoma, Cyclooxygenases, and COX Inhibitors
por: Ganduri, Vinutna, et al.
Publicado: (2022)

Combined Effects of Cyclooxygenase-1 and Cyclooxygenase-2 Selective Inhibitors on Ovarian Carcinoma in Vivo
por: Li, Wei, et al.
Publicado: (2011)

The Endophytic Pseudomonas sp. S57 for Plant-Growth Promotion and the Biocontrol of Phytopathogenic Fungi and Nematodes
por: Muñoz Torres, Patricio, et al.
Publicado: (2021)

Antimetastatic activity of a cyclooxygenase-2 inhibitor
por: Roche-Nagle, G, et al.
Publicado: (2004)

Risk of Cardiovascular Events and Cyclooxygenase-2 Inhibitors
por: Tabrizchi, Reza
Publicado: (2006)

Celecoxib: a selective cyclooxygenase-2 inhibitor
por: Gandelman, M
Publicado: (2003)

Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells
por: Brust, Anja-Kristina, et al.
Publicado: (2008)

Renal Effects of Prostaglandins and Cyclooxygenase-2 Inhibitors
por: Kim, Gheun-Ho
Publicado: (2008)

The cyclooxygenases
por: Chandrasekharan, NV, et al.
Publicado: (2004)

Cyclooxygenase-1-selective inhibitor SC-560
por: Long, Sihui, et al.
Publicado: (2009)

Stimulatory Action of Cyclooxygenase Inhibitors on Hematopoiesis: A Review
por: Hofer, Michal, et al.
Publicado: (2012)

In situ click chemistry generation of cyclooxygenase-2 inhibitors
por: Bhardwaj, Atul, et al.
Publicado: (2017)

Antitumor enhancement of celecoxib, a selective Cyclooxygenase-2 inhibitor, in a Lewis lung carcinoma expressing Cyclooxygenase-2
por: Park, Won, et al.
Publicado: (2008)

Isolation and Identification of Bacteria from Three Geothermal Sites of the Atacama Desert and Their Plant-Beneficial Characteristics
por: Muñoz-Torres, Patricio, et al.
Publicado: (2023)

Tolerance of neurite outgrowth to Rho kinase inhibitors decreased by cyclooxygenase-2 inhibitor☆
por: Duan, Weigang, et al.
Publicado: (2012)

Importance of adherence to gastroprotection during cyclooxygenase 2 inhibitor treatment
por: Gargallo, Carla J., et al.
Publicado: (2013)

Prediction of the potency of mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling
por: Cortes-Ciriano, Isidro, et al.
Publicado: (2015)

Biological Evaluation and Docking Analysis of Daturaolone as Potential Cyclooxygenase Inhibitor
por: Rauf, Abdur, et al.
Publicado: (2016)

Mimosine Dipeptide Enantiomsers: Improved Inhibitors against Melanogenesis and Cyclooxygenase
por: Nguyen, Binh Cao Quan, et al.
Publicado: (2015)

l-Malate (−2) Protonation State is Required for Efficient Decarboxylation to l-Lactate by the Malolactic Enzyme of Oenococcus oeni
por: Acevedo, Waldo, et al.
Publicado: (2020)

Diselenides and Benzisoselenazolones as Antiproliferative Agents and Glutathione-S-Transferase Inhibitors
por: Krasowska, Dorota, et al.
Publicado: (2019)

Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity
por: Fu, Dong-Jun, et al.
Publicado: (2022)

Spherical Harmonics Coefficients for Ligand-Based Virtual Screening of Cyclooxygenase Inhibitors
por: Wang, Quan, et al.
Publicado: (2011)

Use of Selective Cyclooxygenase-2 Inhibitors, Other Analgesics, and Risk of Glioma
por: Seliger, Corinna, et al.
Publicado: (2016)

Molecular Dynamic Screening Sesquiterpenoid Pogostemon Herba as Suggested Cyclooxygenase Inhibitor
por: Raharjo, Sentot Joko, et al.
Publicado: (2016)

Indole Derivatives as Cyclooxygenase Inhibitors: Synthesis, Biological Evaluation and Docking Studies
por: Bhat, Mashooq Ahmad, et al.
Publicado: (2018)

Can a cyclooxygenase inhibitor be an option for treatment of ovarian hyperstimulation syndrome?
por: Çilgin, Hasan
Publicado: (2019)

Safety and potential efficacy of cyclooxygenase‐2 inhibitors in coronavirus disease 2019
por: Ong, Sean Wei Xiang, et al.
Publicado: (2020)

Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells
por: Nemade, Harshal, et al.
Publicado: (2020)

Cyclooxygenase-2 Inhibitor: A Potential Combination Strategy With Immunotherapy in Cancer
por: Pu, Dan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v92dldprfffa0rd2gql4l0vqst