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Replication of Crohn’s Disease Mucosal E. coli Isolates inside Macrophages Correlates with Resistance to Superoxide and Is Dependent on Macrophage NF-kappa B Activation

Mucosa-associated Escherichia coli are increased in Crohn’s disease (CD) and colorectal cancer (CRC). CD isolates replicate within macrophages but the specificity of this effect for CD and its mechanism are unclear. Gentamicin exclusion assay was used to assess E. coli replication within J774.A1 mur...

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Detalles Bibliográficos
Autores principales: Tawfik, Ahmed, Knight, Paul, Duckworth, Carrie A., Pritchard, D. Mark, Rhodes, Jonathan M., Campbell, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630736/
https://www.ncbi.nlm.nih.gov/pubmed/31181736
http://dx.doi.org/10.3390/pathogens8020074