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In silico Designed Ebola Virus T-Cell Multi-Epitope DNA Vaccine Constructions Are Immunogenic in Mice
Background: The lack of effective vaccines against Ebola virus initiates a search for new approaches to overcoming this problem. The aim of the study was to design artificial polyepitope T-cell immunogens—candidate DNA vaccines against Ebola virus and to evaluate their capacity to induce a specific...
Autores principales: | Bazhan, Sergei I., Antonets, Denis V., Karpenko, Larisa I., Oreshkova, Svetlana F., Kaplina, Olga N., Starostina, Ekaterina V., Dudko, Sergei G., Fedotova, Sofia A., Ilyichev, Alexander A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630745/ https://www.ncbi.nlm.nih.gov/pubmed/30934980 http://dx.doi.org/10.3390/vaccines7020034 |
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