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Hosts for Hostile Protein Production: The Challenge of Recombinant Immunotoxin Expression
For the recombinant expression of toxin-based drugs, a crucial step lies not only in the choice of the production host(s) but also in the accurate design of the protein chimera. These issues are particularly important since such products may be toxic to the expressing host itself. To avoid or limit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630761/ https://www.ncbi.nlm.nih.gov/pubmed/31108917 http://dx.doi.org/10.3390/biomedicines7020038 |