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Hosts for Hostile Protein Production: The Challenge of Recombinant Immunotoxin Expression

For the recombinant expression of toxin-based drugs, a crucial step lies not only in the choice of the production host(s) but also in the accurate design of the protein chimera. These issues are particularly important since such products may be toxic to the expressing host itself. To avoid or limit...

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Detalles Bibliográficos
Autores principales: Zuppone, Stefania, Fabbrini, Maria Serena, Vago, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630761/
https://www.ncbi.nlm.nih.gov/pubmed/31108917
http://dx.doi.org/10.3390/biomedicines7020038