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Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses

Drimia indica (Roxb.) Jessop (Asparagaceae) is a reputed Ayurvedic medicine for a number of therapeutic benefits, including for cardiac diseases, indigestion, asthma, dropsy, rheumatism, leprosy, and skin ailments. The present work aimed to critically and extensively review its traditional uses, phy...

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Autores principales: Aswal, Sonali, Kumar, Ankit, Semwal, Ruchi Badoni, Chauhan, Ashutosh, Kumar, Abhimanyu, Lehmann, Jörg, Semwal, Deepak Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630810/
https://www.ncbi.nlm.nih.gov/pubmed/31181697
http://dx.doi.org/10.3390/medicina55060255
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author Aswal, Sonali
Kumar, Ankit
Semwal, Ruchi Badoni
Chauhan, Ashutosh
Kumar, Abhimanyu
Lehmann, Jörg
Semwal, Deepak Kumar
author_facet Aswal, Sonali
Kumar, Ankit
Semwal, Ruchi Badoni
Chauhan, Ashutosh
Kumar, Abhimanyu
Lehmann, Jörg
Semwal, Deepak Kumar
author_sort Aswal, Sonali
collection PubMed
description Drimia indica (Roxb.) Jessop (Asparagaceae) is a reputed Ayurvedic medicine for a number of therapeutic benefits, including for cardiac diseases, indigestion, asthma, dropsy, rheumatism, leprosy, and skin ailments. The present work aimed to critically and extensively review its traditional uses, phytochemistry, pharmacology, toxicology, and taxonomy together with the mechanisms of action of selected extracts of D. indica. A systematic literature survey from scientific databases such as PubMed, Scopus, and Web of Science as well as from some textbooks and classical texts was conducted. The plant, mainly its bulb, contains various bioactive constituents, such as alkylresorcinols, bufadienolides, phytosterols, and flavonoids. Various scientific studies have proven that the plant has anthelmintic, anticancer, antidiabetic, antimicrobial, antioxidant, and wound healing activities. The present work concludes that D. indica has the potential to treat various diseases, mainly microbial infections. This review also suggests that bufadienolides, flavonoids, and steroids might be responsible for its bioactive potential.
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spelling pubmed-66308102019-08-19 Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses Aswal, Sonali Kumar, Ankit Semwal, Ruchi Badoni Chauhan, Ashutosh Kumar, Abhimanyu Lehmann, Jörg Semwal, Deepak Kumar Medicina (Kaunas) Review Drimia indica (Roxb.) Jessop (Asparagaceae) is a reputed Ayurvedic medicine for a number of therapeutic benefits, including for cardiac diseases, indigestion, asthma, dropsy, rheumatism, leprosy, and skin ailments. The present work aimed to critically and extensively review its traditional uses, phytochemistry, pharmacology, toxicology, and taxonomy together with the mechanisms of action of selected extracts of D. indica. A systematic literature survey from scientific databases such as PubMed, Scopus, and Web of Science as well as from some textbooks and classical texts was conducted. The plant, mainly its bulb, contains various bioactive constituents, such as alkylresorcinols, bufadienolides, phytosterols, and flavonoids. Various scientific studies have proven that the plant has anthelmintic, anticancer, antidiabetic, antimicrobial, antioxidant, and wound healing activities. The present work concludes that D. indica has the potential to treat various diseases, mainly microbial infections. This review also suggests that bufadienolides, flavonoids, and steroids might be responsible for its bioactive potential. MDPI 2019-06-07 /pmc/articles/PMC6630810/ /pubmed/31181697 http://dx.doi.org/10.3390/medicina55060255 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Aswal, Sonali
Kumar, Ankit
Semwal, Ruchi Badoni
Chauhan, Ashutosh
Kumar, Abhimanyu
Lehmann, Jörg
Semwal, Deepak Kumar
Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses
title Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses
title_full Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses
title_fullStr Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses
title_full_unstemmed Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses
title_short Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses
title_sort drimia indica: a plant used in traditional medicine and its potential for clinical uses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630810/
https://www.ncbi.nlm.nih.gov/pubmed/31181697
http://dx.doi.org/10.3390/medicina55060255
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