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Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review

In the last decade, several engineered gold-based nanomaterials, such as spheres, rods, stars, cubes, hollow particles, and nanocapsules have been widely explored in biomedical fields, in particular in therapy and diagnostics. As well as different shapes and dimensions, these materials may, on their...

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Detalles Bibliográficos
Autor principal: Venditti, Iole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630817/
https://www.ncbi.nlm.nih.gov/pubmed/31185667
http://dx.doi.org/10.3390/bioengineering6020053
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author Venditti, Iole
author_facet Venditti, Iole
author_sort Venditti, Iole
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description In the last decade, several engineered gold-based nanomaterials, such as spheres, rods, stars, cubes, hollow particles, and nanocapsules have been widely explored in biomedical fields, in particular in therapy and diagnostics. As well as different shapes and dimensions, these materials may, on their surfaces, have specific functionalizations to improve their capability as sensors or in drug loading and controlled release, and/or particular cell receptors ligands, in order to get a definite targeting. In this review, the up-to-date progress will be illustrated regarding morphologies, sizes and functionalizations, mostly used to obtain an improved performance of nanomaterials in biomedicine. Many suggestions are presented to organize and compare the numerous and heterogeneous experimental data, such as the most important chemical-physical parameters, which guide and control the interaction between the gold surface and biological environment. The purpose of all this is to offer the readers an overview of the most noteworthy progress and challenges in this research field.
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spelling pubmed-66308172019-08-19 Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review Venditti, Iole Bioengineering (Basel) Review In the last decade, several engineered gold-based nanomaterials, such as spheres, rods, stars, cubes, hollow particles, and nanocapsules have been widely explored in biomedical fields, in particular in therapy and diagnostics. As well as different shapes and dimensions, these materials may, on their surfaces, have specific functionalizations to improve their capability as sensors or in drug loading and controlled release, and/or particular cell receptors ligands, in order to get a definite targeting. In this review, the up-to-date progress will be illustrated regarding morphologies, sizes and functionalizations, mostly used to obtain an improved performance of nanomaterials in biomedicine. Many suggestions are presented to organize and compare the numerous and heterogeneous experimental data, such as the most important chemical-physical parameters, which guide and control the interaction between the gold surface and biological environment. The purpose of all this is to offer the readers an overview of the most noteworthy progress and challenges in this research field. MDPI 2019-06-10 /pmc/articles/PMC6630817/ /pubmed/31185667 http://dx.doi.org/10.3390/bioengineering6020053 Text en © 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Venditti, Iole
Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review
title Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review
title_full Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review
title_fullStr Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review
title_full_unstemmed Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review
title_short Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review
title_sort engineered gold-based nanomaterials: morphologies and functionalities in biomedical applications. a mini review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630817/
https://www.ncbi.nlm.nih.gov/pubmed/31185667
http://dx.doi.org/10.3390/bioengineering6020053
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