Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H(2)O(2)- and Aβ(1-42)-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells

With the lack of available drugs able to prevent the progression of Alzheimer’s disease (AD), the discovery of new neuroprotective treatments able to rescue neurons from cell injury is presently a matter of extreme importance and urgency. Here, we were inspired by the widely reported potential of na...

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Detalles Bibliográficos
Autores principales: de Matos, Ana M., Martins, Alice, Man, Teresa, Evans, David, Walter, Magnus, Oliveira, Maria Conceição, López, Óscar, Fernandez-Bolaños, José G., Dätwyler, Philipp, Ernst, Beat, Macedo, M. Paula, Contino, Marialessandra, Colabufo, Nicola A., Rauter, Amélia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630837/
https://www.ncbi.nlm.nih.gov/pubmed/31234364
http://dx.doi.org/10.3390/ph12020098

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