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The Adductomics of Isolevuglandins: Oxidation of IsoLG Pyrrole Intermediates Generates Pyrrole–Pyrrole Crosslinks and Lactams

Isoprostane endoperoxides generated by free radical-induced oxidation of arachidonates, and prostaglandin endoperoxides generated through enzymatic cyclooxygenation of arachidonate, rearrange nonenzymatically to isoprostanes and a family of stereo and structurally isomeric γ-ketoaldehyde seco-isopro...

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Detalles Bibliográficos
Autores principales: Bi, Wenzhao, Jang, Geeng-Fu, Zhang, Lei, Crabb, John W., Laird, James, Linetsky, Mikhail, Salomon, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630840/
https://www.ncbi.nlm.nih.gov/pubmed/31083423
http://dx.doi.org/10.3390/ht8020012