Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model

The marked increase in the incidence of melanoma coupled with the rapid drop in the survival rate after metastasis has promoted the investigation into improved diagnostic methods for melanoma. High-frequency ultrasound (US), optical coherence tomography (OCT), and photoacoustic imaging (PAI) are thr...

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Autores principales: Kratkiewicz, Karl, Manwar, Rayyan, Rajabi-Estarabadi, Ali, Fakhoury, Joseph, Meiliute, Jurgita, Daveluy, Steven, Mehregan, Darius, Avanaki, Kamran (Mohammad)
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630987/
https://www.ncbi.nlm.nih.gov/pubmed/31238540
http://dx.doi.org/10.3390/s19122815
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author Kratkiewicz, Karl
Manwar, Rayyan
Rajabi-Estarabadi, Ali
Fakhoury, Joseph
Meiliute, Jurgita
Daveluy, Steven
Mehregan, Darius
Avanaki, Kamran (Mohammad)
author_facet Kratkiewicz, Karl
Manwar, Rayyan
Rajabi-Estarabadi, Ali
Fakhoury, Joseph
Meiliute, Jurgita
Daveluy, Steven
Mehregan, Darius
Avanaki, Kamran (Mohammad)
author_sort Kratkiewicz, Karl
collection PubMed
description The marked increase in the incidence of melanoma coupled with the rapid drop in the survival rate after metastasis has promoted the investigation into improved diagnostic methods for melanoma. High-frequency ultrasound (US), optical coherence tomography (OCT), and photoacoustic imaging (PAI) are three potential modalities that can assist a dermatologist by providing extra information beyond dermoscopic features. In this study, we imaged a swine model with spontaneous melanoma using these modalities and compared the images with images of nearby healthy skin. Histology images were used for validation.
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spelling pubmed-66309872019-08-19 Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model Kratkiewicz, Karl Manwar, Rayyan Rajabi-Estarabadi, Ali Fakhoury, Joseph Meiliute, Jurgita Daveluy, Steven Mehregan, Darius Avanaki, Kamran (Mohammad) Sensors (Basel) Article The marked increase in the incidence of melanoma coupled with the rapid drop in the survival rate after metastasis has promoted the investigation into improved diagnostic methods for melanoma. High-frequency ultrasound (US), optical coherence tomography (OCT), and photoacoustic imaging (PAI) are three potential modalities that can assist a dermatologist by providing extra information beyond dermoscopic features. In this study, we imaged a swine model with spontaneous melanoma using these modalities and compared the images with images of nearby healthy skin. Histology images were used for validation. MDPI 2019-06-24 /pmc/articles/PMC6630987/ /pubmed/31238540 http://dx.doi.org/10.3390/s19122815 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kratkiewicz, Karl
Manwar, Rayyan
Rajabi-Estarabadi, Ali
Fakhoury, Joseph
Meiliute, Jurgita
Daveluy, Steven
Mehregan, Darius
Avanaki, Kamran (Mohammad)
Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model
title Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model
title_full Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model
title_fullStr Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model
title_full_unstemmed Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model
title_short Photoacoustic/Ultrasound/Optical Coherence Tomography Evaluation of Melanoma Lesion and Healthy Skin in a Swine Model
title_sort photoacoustic/ultrasound/optical coherence tomography evaluation of melanoma lesion and healthy skin in a swine model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630987/
https://www.ncbi.nlm.nih.gov/pubmed/31238540
http://dx.doi.org/10.3390/s19122815
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