A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan

Rhabdomyolysis is caused by extensive damage to skeletal muscles resulting in elevated creatine phosphokinase (CPK), Lactate dehydrogenase (LDH), and aspartate aminotransferase (AST), leading to life-threatening consequences like acute renal failure, cardiac arrhythmias, and hyperthermia. A variety...

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Autores principales: Rawla, Prashanth, Raj, Jeffrey Pradeep, George, Sajid Melvin, Nathala, Pavani, Vellipuram, Anantha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631059/
https://www.ncbi.nlm.nih.gov/pubmed/31091647
http://dx.doi.org/10.3390/diseases7020038
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author Rawla, Prashanth
Raj, Jeffrey Pradeep
George, Sajid Melvin
Nathala, Pavani
Vellipuram, Anantha R.
author_facet Rawla, Prashanth
Raj, Jeffrey Pradeep
George, Sajid Melvin
Nathala, Pavani
Vellipuram, Anantha R.
author_sort Rawla, Prashanth
collection PubMed
description Rhabdomyolysis is caused by extensive damage to skeletal muscles resulting in elevated creatine phosphokinase (CPK), Lactate dehydrogenase (LDH), and aspartate aminotransferase (AST), leading to life-threatening consequences like acute renal failure, cardiac arrhythmias, and hyperthermia. A variety of causes for muscle damage are known, and one of the most common is drug-induced. Statins and many other agents are known to induce muscle damage, but here we report Entresto™ (Sacubitril/Valsartan) induced rhabdomyolysis which has not been previously reported as solely responsible in the literature.
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spelling pubmed-66310592019-08-19 A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan Rawla, Prashanth Raj, Jeffrey Pradeep George, Sajid Melvin Nathala, Pavani Vellipuram, Anantha R. Diseases Case Report Rhabdomyolysis is caused by extensive damage to skeletal muscles resulting in elevated creatine phosphokinase (CPK), Lactate dehydrogenase (LDH), and aspartate aminotransferase (AST), leading to life-threatening consequences like acute renal failure, cardiac arrhythmias, and hyperthermia. A variety of causes for muscle damage are known, and one of the most common is drug-induced. Statins and many other agents are known to induce muscle damage, but here we report Entresto™ (Sacubitril/Valsartan) induced rhabdomyolysis which has not been previously reported as solely responsible in the literature. MDPI 2019-05-14 /pmc/articles/PMC6631059/ /pubmed/31091647 http://dx.doi.org/10.3390/diseases7020038 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Rawla, Prashanth
Raj, Jeffrey Pradeep
George, Sajid Melvin
Nathala, Pavani
Vellipuram, Anantha R.
A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan
title A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan
title_full A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan
title_fullStr A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan
title_full_unstemmed A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan
title_short A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan
title_sort rare adverse event of rhabdomyolysis caused by sacubitril/valsartan
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631059/
https://www.ncbi.nlm.nih.gov/pubmed/31091647
http://dx.doi.org/10.3390/diseases7020038
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