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Nasal Administration and Plasma Pharmacokinetics of Parathyroid Hormone Peptide PTH 1-34 for the Treatment of Osteoporosis

Nasal delivery of large peptides such as parathyroid 1-34 (PTH 1-34) can benefit from a permeation enhancer to promote absorption across the nasal mucosa into the bloodstream. Previously, we have published an encouraging bioavailability (78%), relative to subcutaneous injection in a small animal pre...

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Detalles Bibliográficos
Autores principales:	Pearson, Richard G., Masud, Tahir, Blackshaw, Elaine, Naylor, Andrew, Hinchcliffe, Michael, Jeffery, Kirk, Jordan, Faron, Shabir-Ahmed, Anjumn, King, Gareth, Lewis, Andrew L., Illum, Lisbeth, Perkins, Alan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631119/ https://www.ncbi.nlm.nih.gov/pubmed/31181662 http://dx.doi.org/10.3390/pharmaceutics11060265

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