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Species-Specific Conservation of Linear Antigenic Sites on Vaccinia Virus A27 Protein Homologs of Orthopoxviruses

The vaccinia virus (VACV) A27 protein and its homologs, which are found in a large number of members of the genus Orthopoxvirus (OPXV), are targets of viral neutralization by host antibodies. We have mapped six binding sites (epitopes #1A: aa 32–39, #1B: aa 28–33, #1C: aa 26–31, #1D: 28–34, #4: aa 9...

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Detalles Bibliográficos
Autores principales: Ahsendorf, Henrike P., Gan, Li L., Eltom, Kamal H., Abd El Wahed, Ahmed, Hotop, Sven-Kevin, Roper, Rachel L., Beutling, Ulrike, Broenstrup, Mark, Stahl-Hennig, Christiane, Hoelzle, Ludwig E., Czerny, Claus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631127/
https://www.ncbi.nlm.nih.gov/pubmed/31146446
http://dx.doi.org/10.3390/v11060493