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Translational Metabolomics: Current Challenges and Future Opportunities
Metabolomics is one of the latest omics technologies that has been applied successfully in many areas of life sciences. Despite being relatively new, a plethora of publications over the years have exploited the opportunities provided through this data and question driven approach. Most importantly,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631405/ https://www.ncbi.nlm.nih.gov/pubmed/31174372 http://dx.doi.org/10.3390/metabo9060108 |
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author | Pinu, Farhana R. Goldansaz, Seyed Ali Jaine, Jacob |
author_facet | Pinu, Farhana R. Goldansaz, Seyed Ali Jaine, Jacob |
author_sort | Pinu, Farhana R. |
collection | PubMed |
description | Metabolomics is one of the latest omics technologies that has been applied successfully in many areas of life sciences. Despite being relatively new, a plethora of publications over the years have exploited the opportunities provided through this data and question driven approach. Most importantly, metabolomics studies have produced great breakthroughs in biomarker discovery, identification of novel metabolites and more detailed characterisation of biological pathways in many organisms. However, translation of the research outcomes into clinical tests and user-friendly interfaces has been hindered due to many factors, some of which have been outlined hereafter. This position paper is the summary of discussion on translational metabolomics undertaken during a peer session of the Australian and New Zealand Metabolomics Conference (ANZMET 2018) held in Auckland, New Zealand. Here, we discuss some of the key areas in translational metabolomics including existing challenges and suggested solutions, as well as how to expand the clinical and industrial application of metabolomics. In addition, we share our perspective on how full translational capability of metabolomics research can be explored. |
format | Online Article Text |
id | pubmed-6631405 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66314052019-08-19 Translational Metabolomics: Current Challenges and Future Opportunities Pinu, Farhana R. Goldansaz, Seyed Ali Jaine, Jacob Metabolites Perspective Metabolomics is one of the latest omics technologies that has been applied successfully in many areas of life sciences. Despite being relatively new, a plethora of publications over the years have exploited the opportunities provided through this data and question driven approach. Most importantly, metabolomics studies have produced great breakthroughs in biomarker discovery, identification of novel metabolites and more detailed characterisation of biological pathways in many organisms. However, translation of the research outcomes into clinical tests and user-friendly interfaces has been hindered due to many factors, some of which have been outlined hereafter. This position paper is the summary of discussion on translational metabolomics undertaken during a peer session of the Australian and New Zealand Metabolomics Conference (ANZMET 2018) held in Auckland, New Zealand. Here, we discuss some of the key areas in translational metabolomics including existing challenges and suggested solutions, as well as how to expand the clinical and industrial application of metabolomics. In addition, we share our perspective on how full translational capability of metabolomics research can be explored. MDPI 2019-06-06 /pmc/articles/PMC6631405/ /pubmed/31174372 http://dx.doi.org/10.3390/metabo9060108 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Perspective Pinu, Farhana R. Goldansaz, Seyed Ali Jaine, Jacob Translational Metabolomics: Current Challenges and Future Opportunities |
title | Translational Metabolomics: Current Challenges and Future Opportunities |
title_full | Translational Metabolomics: Current Challenges and Future Opportunities |
title_fullStr | Translational Metabolomics: Current Challenges and Future Opportunities |
title_full_unstemmed | Translational Metabolomics: Current Challenges and Future Opportunities |
title_short | Translational Metabolomics: Current Challenges and Future Opportunities |
title_sort | translational metabolomics: current challenges and future opportunities |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631405/ https://www.ncbi.nlm.nih.gov/pubmed/31174372 http://dx.doi.org/10.3390/metabo9060108 |
work_keys_str_mv | AT pinufarhanar translationalmetabolomicscurrentchallengesandfutureopportunities AT goldansazseyedali translationalmetabolomicscurrentchallengesandfutureopportunities AT jainejacob translationalmetabolomicscurrentchallengesandfutureopportunities |