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Translational Metabolomics: Current Challenges and Future Opportunities

Metabolomics is one of the latest omics technologies that has been applied successfully in many areas of life sciences. Despite being relatively new, a plethora of publications over the years have exploited the opportunities provided through this data and question driven approach. Most importantly,...

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Detalles Bibliográficos
Autores principales: Pinu, Farhana R., Goldansaz, Seyed Ali, Jaine, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631405/
https://www.ncbi.nlm.nih.gov/pubmed/31174372
http://dx.doi.org/10.3390/metabo9060108
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author Pinu, Farhana R.
Goldansaz, Seyed Ali
Jaine, Jacob
author_facet Pinu, Farhana R.
Goldansaz, Seyed Ali
Jaine, Jacob
author_sort Pinu, Farhana R.
collection PubMed
description Metabolomics is one of the latest omics technologies that has been applied successfully in many areas of life sciences. Despite being relatively new, a plethora of publications over the years have exploited the opportunities provided through this data and question driven approach. Most importantly, metabolomics studies have produced great breakthroughs in biomarker discovery, identification of novel metabolites and more detailed characterisation of biological pathways in many organisms. However, translation of the research outcomes into clinical tests and user-friendly interfaces has been hindered due to many factors, some of which have been outlined hereafter. This position paper is the summary of discussion on translational metabolomics undertaken during a peer session of the Australian and New Zealand Metabolomics Conference (ANZMET 2018) held in Auckland, New Zealand. Here, we discuss some of the key areas in translational metabolomics including existing challenges and suggested solutions, as well as how to expand the clinical and industrial application of metabolomics. In addition, we share our perspective on how full translational capability of metabolomics research can be explored.
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spelling pubmed-66314052019-08-19 Translational Metabolomics: Current Challenges and Future Opportunities Pinu, Farhana R. Goldansaz, Seyed Ali Jaine, Jacob Metabolites Perspective Metabolomics is one of the latest omics technologies that has been applied successfully in many areas of life sciences. Despite being relatively new, a plethora of publications over the years have exploited the opportunities provided through this data and question driven approach. Most importantly, metabolomics studies have produced great breakthroughs in biomarker discovery, identification of novel metabolites and more detailed characterisation of biological pathways in many organisms. However, translation of the research outcomes into clinical tests and user-friendly interfaces has been hindered due to many factors, some of which have been outlined hereafter. This position paper is the summary of discussion on translational metabolomics undertaken during a peer session of the Australian and New Zealand Metabolomics Conference (ANZMET 2018) held in Auckland, New Zealand. Here, we discuss some of the key areas in translational metabolomics including existing challenges and suggested solutions, as well as how to expand the clinical and industrial application of metabolomics. In addition, we share our perspective on how full translational capability of metabolomics research can be explored. MDPI 2019-06-06 /pmc/articles/PMC6631405/ /pubmed/31174372 http://dx.doi.org/10.3390/metabo9060108 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Pinu, Farhana R.
Goldansaz, Seyed Ali
Jaine, Jacob
Translational Metabolomics: Current Challenges and Future Opportunities
title Translational Metabolomics: Current Challenges and Future Opportunities
title_full Translational Metabolomics: Current Challenges and Future Opportunities
title_fullStr Translational Metabolomics: Current Challenges and Future Opportunities
title_full_unstemmed Translational Metabolomics: Current Challenges and Future Opportunities
title_short Translational Metabolomics: Current Challenges and Future Opportunities
title_sort translational metabolomics: current challenges and future opportunities
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631405/
https://www.ncbi.nlm.nih.gov/pubmed/31174372
http://dx.doi.org/10.3390/metabo9060108
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