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Relation between DNA ionization potentials, single base substitutions and pathogenic variants
BACKGROUND: It is nowadays clear that single base substitutions that occur in the human genome, of which some lead to pathogenic conditions, are non-random and influenced by their flanking nucleobase sequences. However, despite recent progress, the understanding of these "non-local" effect...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631442/ https://www.ncbi.nlm.nih.gov/pubmed/31307386 http://dx.doi.org/10.1186/s12864-019-5867-y |