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TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expression

BACKGROUND: The major limitation of organ transplantation is the shortage of available organs. Xenotransplantation is considered to be an effective way to resolve the problem. Immune rejection is a major hurdle for the successful survival of pig xenografts in primate recipients. Cytokines play impor...

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Detalles Bibliográficos
Autores principales:	Gao, Hanchao, Cao, Mengtao, Chen, Pengfei, Cooper, David K. C., Zhao, Yanli, Wei, Ling, Xu, Jia, Cai, Zhiming, Zeng, Changchun, Luan, Shaodong, Mou, Lisha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631523/ https://www.ncbi.nlm.nih.gov/pubmed/31307477 http://dx.doi.org/10.1186/s12964-019-0386-7

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