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Genome-Guided Discovery of Pretilactam from Actinosynnema pretiosum ATCC 31565

Actinosynnema is a small but well-known genus of actinomycetes for production of ansamitocin, the payload component of antibody-drug conjugates against cancers. However, the secondary metabolite production profile of Actinosynnema pretiosum ATCC 31565, the most famous producer of ansamitocin, has ne...

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Detalles Bibliográficos
Autores principales:	Wang, Jing, Hu, Xiaowen, Sun, Guizhi, Li, Linli, Jiang, Bingya, Li, Shufen, Bai, Liping, Liu, Hongyu, Yu, Liyan, Wu, Linzhuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631532/ https://www.ncbi.nlm.nih.gov/pubmed/31248172 http://dx.doi.org/10.3390/molecules24122281

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