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Piperlongumine Induces Apoptosis and Synergizes with Doxorubicin by Inhibiting the JAK2-STAT3 Pathway in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) lacks major effective target molecules and chemotherapy remains the current main treatment. However, traditional chemotherapy drugs, such as doxorubicin (DOX), cause serious side effects and have a poor prognosis. Piperlongumine (PL), a natural alkaloid, has show...

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Detalles Bibliográficos
Autores principales:	Chen, Di, Ma, Yangmin, Li, Peiqi, Liu, Meng, Fang, Yuan, Zhang, Jiejie, Zhang, Bilin, Hui, Yuyu, Yin, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631638/ https://www.ncbi.nlm.nih.gov/pubmed/31242627 http://dx.doi.org/10.3390/molecules24122338

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