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Litomosoides sp. (Filarioidea: Onchocercidae) Infection in Frugivorous Bats (Artibeus spp.): Pathological Features, Molecular Evidence, and Prevalence

Bats can host pathogenic organisms such as viruses and fungi, but little is known about the pathogenicity of their parasites. Hemoparasites are frequently recorded in Neotropical bats, particularly Litomosoides (Filarioidea: Onchocercidae), but their pathogenic effect on bats is scarcely known. In t...

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Autores principales: Rendón-Franco, Emilio, López-Díaz, Osvaldo, Martínez-Hernández, Fernando, Villalobos, Guiehdani, Muñoz-García, Claudia Irais, Aréchiga-Ceballos, Nidia, Alfonso-Toledo, Jorge Alberto, García Flores, María Martha, Aguilar Setién, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631640/
https://www.ncbi.nlm.nih.gov/pubmed/31083297
http://dx.doi.org/10.3390/tropicalmed4020077
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author Rendón-Franco, Emilio
López-Díaz, Osvaldo
Martínez-Hernández, Fernando
Villalobos, Guiehdani
Muñoz-García, Claudia Irais
Aréchiga-Ceballos, Nidia
Alfonso-Toledo, Jorge Alberto
García Flores, María Martha
Aguilar Setién, Alvaro
author_facet Rendón-Franco, Emilio
López-Díaz, Osvaldo
Martínez-Hernández, Fernando
Villalobos, Guiehdani
Muñoz-García, Claudia Irais
Aréchiga-Ceballos, Nidia
Alfonso-Toledo, Jorge Alberto
García Flores, María Martha
Aguilar Setién, Alvaro
author_sort Rendón-Franco, Emilio
collection PubMed
description Bats can host pathogenic organisms such as viruses and fungi, but little is known about the pathogenicity of their parasites. Hemoparasites are frequently recorded in Neotropical bats, particularly Litomosoides (Filarioidea: Onchocercidae), but their pathogenic effect on bats is scarcely known. In this work, Litomosoides microfilariae were identified in four (8%) out of 51 sampled frugivorous bats belonging to three different species: Artibeus aztecus, Artibeus jamaicensis, and Artibeus lituratus, which are located in Yautepec, Morelos, Mexico. Two infected animals showed weakness, tachypnoea, and ecchymosis on their wings. In these animals, histopathology revealed microfilariae in the blood vessels of the lung, liver, and spleen. Both animals presented exudative pneumonia with congestion and concomitant edema, in addition to moderate arterial hypertrophy. Parasitemia was quantified in blood samples of the infected animals (>3000 parasites/mL). Phylogenetic analysis placed the obtained sequence inside the Litomosoides genus, reaching over 98% identity to the related species. Due to the relevance of bats in ecosystems, any new record of their parasite repertoire offers noteworthy insights into our understanding of the ecology and impact of new parasite species in bats.
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spelling pubmed-66316402019-08-19 Litomosoides sp. (Filarioidea: Onchocercidae) Infection in Frugivorous Bats (Artibeus spp.): Pathological Features, Molecular Evidence, and Prevalence Rendón-Franco, Emilio López-Díaz, Osvaldo Martínez-Hernández, Fernando Villalobos, Guiehdani Muñoz-García, Claudia Irais Aréchiga-Ceballos, Nidia Alfonso-Toledo, Jorge Alberto García Flores, María Martha Aguilar Setién, Alvaro Trop Med Infect Dis Article Bats can host pathogenic organisms such as viruses and fungi, but little is known about the pathogenicity of their parasites. Hemoparasites are frequently recorded in Neotropical bats, particularly Litomosoides (Filarioidea: Onchocercidae), but their pathogenic effect on bats is scarcely known. In this work, Litomosoides microfilariae were identified in four (8%) out of 51 sampled frugivorous bats belonging to three different species: Artibeus aztecus, Artibeus jamaicensis, and Artibeus lituratus, which are located in Yautepec, Morelos, Mexico. Two infected animals showed weakness, tachypnoea, and ecchymosis on their wings. In these animals, histopathology revealed microfilariae in the blood vessels of the lung, liver, and spleen. Both animals presented exudative pneumonia with congestion and concomitant edema, in addition to moderate arterial hypertrophy. Parasitemia was quantified in blood samples of the infected animals (>3000 parasites/mL). Phylogenetic analysis placed the obtained sequence inside the Litomosoides genus, reaching over 98% identity to the related species. Due to the relevance of bats in ecosystems, any new record of their parasite repertoire offers noteworthy insights into our understanding of the ecology and impact of new parasite species in bats. MDPI 2019-05-10 /pmc/articles/PMC6631640/ /pubmed/31083297 http://dx.doi.org/10.3390/tropicalmed4020077 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rendón-Franco, Emilio
López-Díaz, Osvaldo
Martínez-Hernández, Fernando
Villalobos, Guiehdani
Muñoz-García, Claudia Irais
Aréchiga-Ceballos, Nidia
Alfonso-Toledo, Jorge Alberto
García Flores, María Martha
Aguilar Setién, Alvaro
Litomosoides sp. (Filarioidea: Onchocercidae) Infection in Frugivorous Bats (Artibeus spp.): Pathological Features, Molecular Evidence, and Prevalence
title Litomosoides sp. (Filarioidea: Onchocercidae) Infection in Frugivorous Bats (Artibeus spp.): Pathological Features, Molecular Evidence, and Prevalence
title_full Litomosoides sp. (Filarioidea: Onchocercidae) Infection in Frugivorous Bats (Artibeus spp.): Pathological Features, Molecular Evidence, and Prevalence
title_fullStr Litomosoides sp. (Filarioidea: Onchocercidae) Infection in Frugivorous Bats (Artibeus spp.): Pathological Features, Molecular Evidence, and Prevalence
title_full_unstemmed Litomosoides sp. (Filarioidea: Onchocercidae) Infection in Frugivorous Bats (Artibeus spp.): Pathological Features, Molecular Evidence, and Prevalence
title_short Litomosoides sp. (Filarioidea: Onchocercidae) Infection in Frugivorous Bats (Artibeus spp.): Pathological Features, Molecular Evidence, and Prevalence
title_sort litomosoides sp. (filarioidea: onchocercidae) infection in frugivorous bats (artibeus spp.): pathological features, molecular evidence, and prevalence
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631640/
https://www.ncbi.nlm.nih.gov/pubmed/31083297
http://dx.doi.org/10.3390/tropicalmed4020077
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