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Macrophage-derived exosomal microRNA-501-3p promotes progression of pancreatic ductal adenocarcinoma through the TGFBR3-mediated TGF-β signaling pathway

BACKGROUND: Exosomes from cancer cells or immune cells, carrying bio-macromolecules or microRNAs (miRNAs), participate in tumor pathogenesis and progression by modulating microenvironment. Our study aims to investigate the role of these microRNA-501-3p (miR-501-3p) containing exosomes derived from t...

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Detalles Bibliográficos
Autores principales: Yin, Zi, Ma, Tingting, Huang, Bowen, Lin, Lehang, Zhou, Yu, Yan, Jinhai, Zou, Yiping, Chen, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631643/
https://www.ncbi.nlm.nih.gov/pubmed/31307515
http://dx.doi.org/10.1186/s13046-019-1313-x