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Aβ(M1–40) and Wild-Type Aβ40 Self-Assemble into Oligomers with Distinct Quaternary Structures

Amyloid-β oligomers (AβOs) self-assemble into polymorphic species with diverse biological activities that are implicated causally to Alzheimer’s disease (AD). Synaptotoxicity of AβO species is dependent on their quaternary structure, however, low-abundance and environmental sensitivity of AβOs in vi...

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Detalles Bibliográficos
Autores principales: Bouchard, Jacob L., Davey, Taylor C., Doran, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631858/
https://www.ncbi.nlm.nih.gov/pubmed/31208071
http://dx.doi.org/10.3390/molecules24122242

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