Cargando…
Aβ(M1–40) and Wild-Type Aβ40 Self-Assemble into Oligomers with Distinct Quaternary Structures
Amyloid-β oligomers (AβOs) self-assemble into polymorphic species with diverse biological activities that are implicated causally to Alzheimer’s disease (AD). Synaptotoxicity of AβO species is dependent on their quaternary structure, however, low-abundance and environmental sensitivity of AβOs in vi...
Autores principales: | Bouchard, Jacob L., Davey, Taylor C., Doran, Todd M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631858/ https://www.ncbi.nlm.nih.gov/pubmed/31208071 http://dx.doi.org/10.3390/molecules24122242 |
Ejemplares similares
-
Anti-Parallel β-Hairpin Structure in Soluble Aβ Oligomers of Aβ40-Dutch and Aβ40-Iowa
por: Fu, Ziao, et al.
Publicado: (2021) -
Spontaneous self-assembly of amyloid β (1–40) into dimers
por: Hashemi, Mohtadin, et al.
Publicado: (2019) -
Amyloid β-peptides 1–40 and 1–42 form oligomers with mixed β-sheets
por: Baldassarre, Maurizio, et al.
Publicado: (2017) -
Environmental Factors Preceding Aβ40 Monomer to Oligomers and the Detection of Oligomers in Alzheimer's Disease Patient Serum
por: Matsunaga, Yoichi, et al.
Publicado: (2012) -
Aβ40 Oligomers Identified as a Potential Biomarker for the Diagnosis of Alzheimer's Disease
por: Gao, Carol Man, et al.
Publicado: (2010)