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Animal to human translation: a systematic scoping review of reported concordance rates
BACKGROUND: Drug development is currently hampered by high attrition rates; many developed treatments fail during clinical testing. Part of the attrition may be due to low animal-to-human translational success rates; so-called “translational failure”. As far as we know, no systematic overview of pub...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631915/ https://www.ncbi.nlm.nih.gov/pubmed/31307492 http://dx.doi.org/10.1186/s12967-019-1976-2 |