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Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo

BACKGROUND: While multiagent chemotherapy has dramatically improved the prognosis of sarcoma, the novel chemotherapeutics have hardly developed over the past 30 years. Caffeine can induce apoptosis, delays in cell cycle progression and can enhance the cytocidal effects of anti-cancer agents. Citrate...

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Detalles Bibliográficos
Autores principales:	Abe, Kensaku, Yamamoto, Norio, Hayashi, Katsuhiro, Takeuchi, Akihiko, Tsuchiya, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631922/ https://www.ncbi.nlm.nih.gov/pubmed/31307409 http://dx.doi.org/10.1186/s12885-019-5891-y

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