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Assessing cell-specific effects of genetic variations using tRNA microarrays

BACKGROUND: By definition, effect of synonymous single-nucleotide variants (SNVs) on protein folding and function are neutral, as they alter the codon and not the encoded amino acid. Recent examples indicate tissue-specific and transfer RNA (tRNA)-dependent effects of some genetic variations arguing...

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Detalles Bibliográficos
Autores principales:	Polte, Christine, Wedemeyer, Daniel, Oliver, Kathryn E., Wagner, Johannes, Bijvelds, Marcel J. C., Mahoney, John, de Jonge, Hugo R., Sorscher, Eric J., Ignatova, Zoya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632033/ https://www.ncbi.nlm.nih.gov/pubmed/31307398 http://dx.doi.org/10.1186/s12864-019-5864-1

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