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CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism

BACKGROUND: Mitochondrial oxidative phosphorylation (OXPHOS) via the respiratory chain is required for the maintenance of tumour cell proliferation and regulation of epithelial to mesenchymal transition (EMT)-related phenotypes through mechanisms that are not fully understood. The essential mitochon...

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Detalles Bibliográficos
Autores principales:	Thomas, Luke W., Esposito, Cinzia, Stephen, Jenna M., Costa, Ana S. H., Frezza, Christian, Blacker, Thomas S., Szabadkai, Gyorgy, Ashcroft, Margaret
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632184/ https://www.ncbi.nlm.nih.gov/pubmed/31346464 http://dx.doi.org/10.1186/s40170-019-0200-4

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