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Impact of uPA/PAI-1 and disseminated cytokeratin-positive cells in breast cancer

BACKGROUND: The protease uPA and its inhibitor PAI-1 play major roles in hemostasis and are also involved in cancer progression. This is mainly caused by their ability to degrade extracellular matrix-facilitating tumor cell migration. This study aimed to investigate the impact of uPA/PAI-1 and disse...

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Detalles Bibliográficos
Autores principales: Märkl, Bruno, Kazik, Martin, Harbeck, Nadia, Jakubowicz, Elzbieta, Hoffmann, Reinhard, Jung, Thomas, Steinfeld, Dieter, Schenkirsch, Gerhard, Schlimok, Günter, Oruzio, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632216/
https://www.ncbi.nlm.nih.gov/pubmed/31307406
http://dx.doi.org/10.1186/s12885-019-5857-0