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Synthesis and biological evaluation of truncated derivatives of abyssomicin C as antibacterial agents

The synthesis and antibacterial activity of two new highly truncated derivatives of the natural product abyssomicin C are reported. This work outlines the limits of structural truncation of the natural product and consequently provides insights for further structure–activity relationship studies tow...

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Detalles Bibliográficos
Autores principales: Monjas, Leticia, Fodran, Peter, Kollback, Johanna, Cassani, Carlo, Olsson, Thomas, Genheden, Maja, Larsson, D G Joakim, Wallentin, Carl-Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633193/
https://www.ncbi.nlm.nih.gov/pubmed/31354863
http://dx.doi.org/10.3762/bjoc.15.147