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Strategies for genetic inactivation of long noncoding RNAs in zebrafish

The number of annotated long noncoding RNAs (lncRNAs) continues to grow; however, their functional characterization in model organisms has been hampered by the lack of reliable genetic inactivation strategies. While partial or full deletions of lncRNA loci disrupt lncRNA expression, they do not perm...

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Detalles Bibliográficos
Autores principales: Lavalou, Perrine, Eckert, Helene, Damy, Louise, Constanty, Florian, Majello, Sara, Bitetti, Angelo, Graindorge, Antoine, Shkumatava, Alena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633201/
https://www.ncbi.nlm.nih.gov/pubmed/31043511
http://dx.doi.org/10.1261/rna.069484.118