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Ca(2+) entry via TRPC1 is essential for cellular differentiation and modulates secretion via the SNARE complex
Properties of adipocytes, including differentiation and adipokine secretion, are crucial factors in obesity-associated metabolic syndrome. Here, we provide evidence that Ca(2+) influx in primary adipocytes, especially upon Ca(2+) store depletion, plays an important role in adipocyte differentiation,...
Autores principales: | Schaar, Anne, Sun, Yuyang, Sukumaran, Pramod, Rosenberger, Thad A., Krout, Danielle, Roemmich, James N., Brinbaumer, Lutz, Claycombe-Larson, Kate, Singh, Brij B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397/ https://www.ncbi.nlm.nih.gov/pubmed/31182642 http://dx.doi.org/10.1242/jcs.231878 |
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