Cargando…
Small-molecule targeting of brachyury transcription factor addiction in chordoma
Autores principales: | Sharifnia, Tanaz, Wawer, Mathias J., Chen, Ting, Huang, Qing-Yuan, Weir, Barbara A., Sizemore, Ann, Lawlor, Matthew A., Goodale, Amy, Cowley, Glenn S., Vazquez, Francisca, Ott, Christopher J., Francis, Joshua M., Sassi, Slim, Cogswell, Patricia, Sheppard, Hadley E., Zhang, Tinghu, Gray, Nathanael S., Clarke, Paul A., Blagg, Julian, Workman, Paul, Sommer, Josh, Hornicek, Francis, Root, David E., Hahn, William C., Bradner, James E., Wong, Kwok K., Clemons, Paul A., Lin, Charles Y., Kotz, Joanne D., Schreiber, Stuart L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633917/ https://www.ncbi.nlm.nih.gov/pubmed/30664779 http://dx.doi.org/10.1038/s41591-018-0312-3 |
Ejemplares similares
-
Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
por: Sheppard, Hadley E., et al.
Publicado: (2021) -
Mapping the landscape of genetic dependencies in chordoma
por: Sharifnia, Tanaz, et al.
Publicado: (2023) -
Tissue Microarray Immunohistochemical Detection of Brachyury Is Not a Prognostic Indicator in Chordoma
por: Zhang, Linlin, et al.
Publicado: (2013) -
From Notochord Formation to Hereditary Chordoma: The Many Roles of Brachyury
por: Nibu, Yutaka, et al.
Publicado: (2013) -
Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
por: D'Agati, Gianluca, et al.
Publicado: (2019)