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Ezrin promotes pancreatic cancer cell proliferation and invasion through activating the Akt/mTOR pathway and inducing YAP translocation

BACKGROUND: Ezrin and YAP are abnormally expressed in various cancers, and play pivotal roles in cancer initiation and development. However, the mechanisms of Ezrin in pancreatic cancer have not been fully elucidated. In this study, we aimed to elucidate the functions and mechanisms of Ezrin in the...

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Detalles Bibliográficos
Autores principales: Quan, Chunji, Sun, Jie, Lin, Zhenhua, Jin, Tiefeng, Dong, Bing, Meng, Ziqi, Piao, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634270/
https://www.ncbi.nlm.nih.gov/pubmed/31372056
http://dx.doi.org/10.2147/CMAR.S202342