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Ezrin promotes pancreatic cancer cell proliferation and invasion through activating the Akt/mTOR pathway and inducing YAP translocation
BACKGROUND: Ezrin and YAP are abnormally expressed in various cancers, and play pivotal roles in cancer initiation and development. However, the mechanisms of Ezrin in pancreatic cancer have not been fully elucidated. In this study, we aimed to elucidate the functions and mechanisms of Ezrin in the...
Autores principales: | Quan, Chunji, Sun, Jie, Lin, Zhenhua, Jin, Tiefeng, Dong, Bing, Meng, Ziqi, Piao, Junjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634270/ https://www.ncbi.nlm.nih.gov/pubmed/31372056 http://dx.doi.org/10.2147/CMAR.S202342 |
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